Item Type | Name |
Concept
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DNA-Binding Proteins
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Academic Article
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The Id2 gene is a novel target of transcriptional activation by EWS-ETS fusion proteins in Ewing family tumors.
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Academic Article
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Overexpression of peptidyl-prolyl isomerase-like 1 is associated with the growth of colon cancer cells.
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Academic Article
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Proliferation potential-related protein, an ideal esophageal cancer antigen for immunotherapy, identified using complementary DNA microarray analysis.
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Academic Article
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Activation of WD repeat and high-mobility group box DNA binding protein 1 in pulmonary and esophageal carcinogenesis.
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Academic Article
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The association of a nonsynonymous single-nucleotide polymorphism in TNFAIP3 with systemic lupus erythematosus and rheumatoid arthritis in the Japanese population.
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Academic Article
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A genome-wide association study identified AFF1 as a susceptibility locus for systemic lupus eyrthematosus in Japanese.
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Academic Article
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Enhanced expression of RAD51 associating protein-1 is involved in the growth of intrahepatic cholangiocarcinoma cells.
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Academic Article
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Genetic variations in the gene encoding TFAP2B are associated with type 2 diabetes mellitus.
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Academic Article
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Integration of cell line and clinical trial genome-wide analyses supports a polygenic architecture of Paclitaxel-induced sensory peripheral neuropathy.
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Academic Article
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An intronic SNP in a RUNX1 binding site of SLC22A4, encoding an organic cation transporter, is associated with rheumatoid arthritis.
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Academic Article
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Association of a single-nucleotide polymorphism in the immunoglobulin mu-binding protein 2 gene with immunoglobulin A nephropathy.
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Academic Article
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C12orf48, termed PARP-1 binding protein, enhances poly(ADP-ribose) polymerase-1 (PARP-1) activity and protects pancreatic cancer cells from DNA damage.
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Academic Article
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Validation of the histone methyltransferase EZH2 as a therapeutic target for various types of human cancer and as a prognostic marker.
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Academic Article
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Identification of a novel oncogene, MMS22L, involved in lung and esophageal carcinogenesis.
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Academic Article
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Association between obesity and polymorphisms in SEC16B, TMEM18, GNPDA2, BDNF, FAIM2 and MC4R in a Japanese population.
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Academic Article
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Identification of the interferon regulatory factor 5 gene (IRF-5) as a direct target for p53.
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Academic Article
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Large-scale screening of TARDBP mutation in amyotrophic lateral sclerosis in Japanese.
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Academic Article
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ICBP90, an E2F-1 target, recruits HDAC1 and binds to methyl-CpG through its SRA domain.
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Academic Article
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A novel oncoprotein RNF43 functions in an autocrine manner in colorectal cancer.
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Academic Article
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Involvement of FKHR-dependent TRADD expression in chemotherapeutic drug-induced apoptosis.
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Academic Article
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Identification of a novel human gene, ZFP91, involved in acute myelogenous leukemia.
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Academic Article
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Up-regulation of PSF2, a member of the GINS multiprotein complex, in intrahepatic cholangiocarcinoma.
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Academic Article
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Selective estrogen receptor modulators and pharmacogenomic variation in ZNF423 regulation of BRCA1 expression: individualized breast cancer prevention.
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Academic Article
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Activation of Holliday junction recognizing protein involved in the chromosomal stability and immortality of cancer cells.
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Academic Article
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PCOTH, a novel gene overexpressed in prostate cancers, promotes prostate cancer cell growth through phosphorylation of oncoprotein TAF-Ibeta/SET.
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Academic Article
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Polymorphisms in the 3' UTR in the neurocalcin delta gene affect mRNA stability, and confer susceptibility to diabetic nephropathy.
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Academic Article
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EGR2 induces apoptosis in various cancer cell lines by direct transactivation of BNIP3L and BAK.
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Academic Article
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Nucleobindin 1 controls the unfolded protein response by inhibiting ATF6 activation.
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Academic Article
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Involvement of PEG10 in human hepatocellular carcinogenesis through interaction with SIAH1.
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Academic Article
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Involvement of the FGF18 gene in colorectal carcinogenesis, as a novel downstream target of the beta-catenin/T-cell factor complex.
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Academic Article
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Identification of SP5 as a downstream gene of the beta-catenin/Tcf pathway and its enhanced expression in human colon cancer.
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Academic Article
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Minichromosome Maintenance Protein 7 is a potential therapeutic target in human cancer and a novel prognostic marker of non-small cell lung cancer.
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Academic Article
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Determination of splice-site mutations in Lynch syndrome (hereditary non-polyposis colorectal cancer) patients using functional splicing assay.
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Academic Article
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Methylation at CpG islands in intron 1 of EGR2 confers enhancer-like activity.
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Academic Article
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Identification of BMP and activin membrane-bound inhibitor (BAMBI), an inhibitor of transforming growth factor-beta signaling, as a target of the beta-catenin pathway in colorectal tumor cells.
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Academic Article
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Identification of a nuclear protein, LRRC42, involved in lung carcinogenesis.
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Academic Article
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The p53 family member genes are involved in the Notch signal pathway.
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Academic Article
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Identification of the interleukin 4 receptor alpha gene as a direct target for p73.
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Academic Article
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Oncogenic role of KIAA0101 interacting with proliferating cell nuclear antigen in pancreatic cancer.
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Academic Article
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Identification of pigment epithelium-derived factor as a direct target of the p53 family member genes.
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Academic Article
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HJURP is a cell-cycle-dependent maintenance and deposition factor of CENP-A at centromeres.
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Academic Article
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A phase I clinical trial of RNF43 peptide-related immune cell therapy combined with low-dose cyclophosphamide in patients with advanced solid tumors.
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